OTUB2 Antibody

• Background:

  Otubains are deubiquitylating cysteine proteases (DUBs; see MIM 602519) that belong to the ovarian tumor (OTU) protein superfamily. Like other DUBs, otubains cleave proteins precisely at the ubiquitin (UB; see MIM 191339) -protein bond.

• NCBI Gene ID:

  78990

• Swiss Prot:

  Q96DC9

• Accession Number:

  Q96DC9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This OTUB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human OTUB2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  27 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  OTUB2

• NCBI Official Name:

  Ubiquitin thioesterase OTUB2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, S., et al. J. Biol. Chem. 285 (7) :4291-4297 (2010)

• Background Reference 02:

  Sowa, M.E., et al. Cell 138 (2) :389-403 (2009)

• Background Reference 03:

  Edelmann, M.J., et al. Biochem. J. 418 (2) :379-390 (2009)

• Background Reference 04:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names:

  Ubiquitin thioesterase OTUB2, Deubiquitinating enzyme OTUB2, OTU domain-containing ubiquitin aldehyde-binding protein 2, Otubain-2, Ubiquitin-specific-processing protease OTUB2, OTUB2, C14orf137, OTB2, OTU2

• Tested Applications:

  WB

• Protein ID:

  44888285

• Physical Properties:

  Liquid