PPEF1 Antibody

• Background:

  This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate (s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described.

• NCBI Gene ID:

  5475

• Swiss Prot:

  O14829

• Accession Number:

  O14829

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-327 amino acids from the Central region of human PPEF1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  76 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPEF1

• NCBI Official Name:

  Serine/threonine-protein phosphatase with EF-hands 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

• Background Reference 02:

  Hillman, R.T., et al. Genome Biol. (2), R8 (2004) :

• Background Reference 03:

  Gevaert, K., et al. Nat. Biotechnol. 21 (5) :566-569 (2003)

• Background Reference 04:

  Kutuzov, M.A., et al. Biochem. Biophys. Res. Commun. 293 (3) :1047-1052 (2002)

• Other Product Names:

  Serine/threonine-protein phosphatase with EF-hands 1, PPEF-1, Protein phosphatase with EF calcium-binding domain, PPEF, Serine/threonine-protein phosphatase 7, PP7, PPEF1, PPEF, PPP7C

• Tested Applications:

  WB

• Physical Properties:

  Liquid