TAC3 Antibody

CAT: 0223-57-679Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-679Size:400 µL
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Background
This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
6866
Swiss Prot
Q9UHF0
Accession Number
Q9UHF0
Host
Rabbit
Reactivity
Human
Immunogen
This TAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the Central region of human TAC3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
13 kDa
Fragment
Rabbit Ig
Symbol
TAC3
NCBI Official Name
Tachykinin-3
NCBI Organism
Homo sapiens
Background Reference 01
Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :
Background Reference 02
Hrabovszky, E., et al. Eur. J. Neurosci. 31 (11) :1984-1998 (2010)
Background Reference 03
Gianetti, E., et al. J. Clin. Endocrinol. Metab. 95 (6) :2857-2867 (2010)
Background Reference 04
Young, J., et al. J. Clin. Endocrinol. Metab. 95 (5) :2287-2295 (2010)
Other Product Names
Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB
Tested Applications
WB, IHC-P
Protein ID
18203501
Physical Properties
Liquid

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