TAC4 Antibody

• Background:

  This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  255061

• Swiss Prot:

  Q86UU9

• Accession Number:

  Q86UU9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TAC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TAC4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  12 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TAC4

• NCBI Official Name:

  Tachykinin-4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :

• Background Reference 02:

  Tran, A.H., et al. Neuropeptides 43 (1) :1-12 (2009)

• Background Reference 03:

  Cunningham, S., et al. J. Neuroimmunol. 183 (1-2), 208-213 (2007) :

• Background Reference 04:

  Page, N.M. Vascul. Pharmacol. 45 (4) :200-208 (2006)

• Other Product Names:

  HGNC:16641

• Tested Applications:

  WB

• Protein ID:

  74723510

• Physical Properties:

  Liquid