M Cadherin Antibody

• Background:

  CDH15 is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. This protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.

• NCBI Gene ID:

  1013

• Swiss Prot:

  P55291

• Accession Number:

  P55291

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This M Cadherin (CDH15) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 739-767 amino acids from the C-terminal region of human M Cadherin (CDH15) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  89 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CDH15

• NCBI Official Name:

  Cadherin-15

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kang, J.S., Proc. Natl. Acad. Sci. U.S.A. 100 (7), 3989-3994 (2003) Hollnagel, A., Mol. Cell. Biol. 22 (13), 4760-4770 (2002) Meigs, T.E., Proc. Natl. Acad. Sci. U.S.A. 98 (2), 519-524 (2001)

• Other Product Names:

  Cadherin-15, Cadherin-14, Muscle cadherin, M-cadherin, CDH15, CDH14, CDH3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  1705553

• Physical Properties:

  Liquid