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XRN2 Antibody

CAT: 0223-57-673Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-673Size:400 µL
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Background
This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known.
NCBI Gene ID
22803
Swiss Prot
Q9H0D6
Accession Number
Q9H0D6
Host
Rabbit
Reactivity
Human
Immunogen
This XRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human XRN2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Drosophila, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
109 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
XRN2
NCBI Official Name
5'-3' exoribonuclease 2
NCBI Organism
Homo sapiens
Background Reference 01
Lu, Y., et al. Oncogene 29 (7) :1041-1049 (2010)
Background Reference 02
Yang, X.C., et al. Mol. Cell. Biol. 29 (1) :31-42 (2009)
Background Reference 03
Kaneko, S., et al. Genes Dev. 21 (14) :1779-1789 (2007)
Background Reference 04
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Other Product Names
5'-3' exoribonuclease 2, 3113-, DHM1-like protein, DHP protein, XRN2
Tested Applications
WB
Protein ID
30173484
Physical Properties
Liquid

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