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SMARCE1 Antibody

CAT: 0223-57-670Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-670Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
NCBI Gene ID
6605
Swiss Prot
Q969G3
Accession Number
Q969G3
Host
Rabbit
Reactivity
Human
Immunogen
This SMARCE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-335 amino acids from the C-terminal region of human SMARCE1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
SMARCE1
NCBI Official Name
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
NCBI Organism
Homo sapiens
Background Reference 01
Hah, N., et al. Cancer Res. 70 (11) :4402-4411 (2010)
Background Reference 02
Barrett, J.C., et al. Nat. Genet. 41 (6) :703-707 (2009)
Background Reference 03
Pan, H., et al. Biochim. Biophys. Acta 1772 (9) :1075-1084 (2007)
Background Reference 04
Camargo, L.M., et al. Mol. Psychiatry 12 (1) :74-86 (2007)
Other Product Names
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1, BRG1-associated factor 57, BAF57, SMARCE1, BAF57
Tested Applications
WB, IHC-P
Protein ID
61247587
Physical Properties
Liquid

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