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SMARCB1 Antibody

CAT: 0223-57-668Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-668Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
NCBI Gene ID
6598
Swiss Prot
Q12824
Accession Number
Q12824
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This SMARCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human SMARCB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SMARCB1
NCBI Official Name
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
NCBI Organism
Homo sapiens
Background Reference 01
Bakshi, R., et al. J. Cell. Physiol. 225 (2) :569-576 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Hadfield, K.D., et al. J. Med. Genet. 47 (8) :567-568 (2010)
Background Reference 04
Kohashi, K., et al. Mod. Pathol. 23 (7) :981-990 (2010)
Other Product Names
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, BRG1-associated factor 47, BAF47, Integrase interactor 1 protein, SNF5 homolog, hSNF5, SMARCB1, BAF47, INI1, SNF5L1
Tested Applications
WB
Protein ID
51338799
Physical Properties
Liquid

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