SMARCC1 Antibody

• Background:

  SMARCC1 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.

• NCBI Gene ID:

  6599

• Swiss Prot:

  Q92922

• Accession Number:

  NP_003065

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMARCC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMARCC1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  123 kDa

• Applications Notes:

  SMARCC1 antibody can be used for detection of SMARCC1 by ELISA at 1:312500. SMARCC1 antibody can be used for detection of SMARCC1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SMARCC1

• NCBI Official Name:

  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Phelan, M.L., et al., (1999) Mol. Cell 3 (2), 247-253.

• Other Product Names:

  SMARCC1, Rsc8, SRG3, SWI3, BAF155, CRACC1

• Tested Applications:

  ELISA, WB

• Protein ID:

  188536047

• Physical Properties:

  Liquid