Desmin Antibody

• Background:

  This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq].

• NCBI Gene ID:

  1674

• Swiss Prot:

  P17661

• Accession Number:

  P17661

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Desmin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-359 amino acids from the C-terminal region of human Desmin.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  54 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  DES

• NCBI Official Name:

  Desmin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Van Spaendonck-Zwarts, K., et al. Clin. Genet. (2010) In press :

• Background Reference 03:

  Zimmerman, R.S., et al. Genet. Med. 12 (5) :268-278 (2010)

• Background Reference 04:

  Bar, H., et al. J. Mol. Biol. 397 (5) :1188-1198 (2010)

• Other Product Names:

  Desmin, DES

• Tested Applications:

  WB, IHC-P

• Protein ID:

  6686280

• Physical Properties:

  Liquid