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OTU7B Antibody

CAT: 0223-57-615Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-615Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OTU7B has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.
NCBI Gene ID
56957
Swiss Prot
Q6GQQ9
Accession Number
Q6GQQ9
Host
Rabbit
Reactivity
Human
Immunogen
This OTU7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 757-784 amino acids from the C-terminal region of human OTU7B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
93 kDa
Fragment
Rabbit Ig
Symbol
OTUD7B
NCBI Official Name
OTU domain-containing protein 7B
NCBI Organism
Homo sapiens
Background Reference 01
Bremm, A., et al. Nat. Struct. Mol. Biol. 17 (8) :939-947 (2010)
Background Reference 02
Jin, Z., et al. Cell 137 (4) :721-735 (2009)
Background Reference 03
Enesa, K., et al. J. Biol. Chem. 283 (27) :18582-18590 (2008)
Background Reference 04
Bohgaki, M., et al. Biochim. Biophys. Acta 1783 (5) :826-837 (2008)
Other Product Names
OTU domain-containing protein 7B, Cellular zinc finger anti-NF-kappa-B protein, Zinc finger A20 domain-containing protein 1, Zinc finger protein Cezanne, OTUD7B, ZA20D1
Tested Applications
WB, IHC-P
Protein ID
51701318
Physical Properties
Liquid

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