Mouse Raf1 Antibody

CAT: 0223-57-614Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-614Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3 (By similarity) .
NCBI Gene ID
110157
Swiss Prot
Q99N57
Accession Number
Q99N57
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Raf1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-113 amino acids from the N-terminal region of mouse Raf1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Symbol
Raf1
NCBI Official Name
RAF proto-oncogene serine/threonine-protein kinase
NCBI Organism
Mus musculus
Background Reference 01
Niault, T.S., et al. Carcinogenesis 31 (7) :1165-1174 (2010)
Background Reference 02
Batarseh, A., et al. Biochemistry 49 (23) :4766-4778 (2010)
Background Reference 03
Tarutani, M., et al. J. Dermatol. Sci. 58 (1) :28-35 (2010)
Background Reference 04
Heidorn, S.J., et al. Cell 140 (2) :209-221 (2010)
Other Product Names
RAF proto-oncogene serine/threonine-protein kinase, Proto-oncogene c-RAF, cRaf, Raf-1, Raf1, Craf
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid

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