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Mouse Irak3 Antibody

CAT: 0223-57-600Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-600Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Irak3 inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
NCBI Gene ID
73914
Swiss Prot
Q8K4B2
Accession Number
Q8K4B2
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Irak3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517-544 amino acids from the C-terminal region of mouse Irak3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Irak3
NCBI Official Name
Interleukin-1 receptor-associated kinase 3
NCBI Organism
Mus musculus
Background Reference 01
Turnis, M.E., et al. J. Immunol. 185 (7) :4223-4232 (2010)
Background Reference 02
Hubbard, L.L., et al. J. Immunol. 184 (11) :6299-6308 (2010)
Background Reference 03
Seki, M., et al. J. Immunol. 184 (3) :1410-1418 (2010)
Background Reference 04
Lyn-Kew, K., et al. PLoS ONE (6), E11145 (2010) :
Other Product Names
Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M, Irak3 {ECO:0000312|MGI:MGI:1921164}
Tested Applications
WB
Physical Properties
Liquid

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