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Mouse Irak4 Antibody

CAT: 0223-57-510Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-510Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity) .
NCBI Gene ID
266632
Swiss Prot
Q8R4K2
Accession Number
Q8R4K2
Host
Rabbit
Reactivity
Human
Immunogen
This Mouse Irak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-449 amino acids from the C-terminal region of mouse Irak4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Irak4
NCBI Official Name
Interleukin-1 receptor-associated kinase 4
NCBI Organism
Mus musculus
Background Reference 01
Erdman, L.K., et al. J. Immunol. 183 (10) :6452-6459 (2009)
Background Reference 02
Maekawa, Y., et al. Circulation 120 (14) :1401-1414 (2009)
Background Reference 03
Bauernfeind, F.G., et al. J. Immunol. 183 (2) :787-791 (2009)
Background Reference 04
Staschke, K.A., et al. J. Immunol. 183 (1) :568-577 (2009)
Other Product Names
Interleukin-1 receptor-associated kinase 4, IRAK-4, Irak4
Tested Applications
WB
Physical Properties
Liquid

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