RGS9 Antibody

• Background:

  This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  8787

• Swiss Prot:

  O75916

• Accession Number:

  O75916

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RGS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the N-terminal region of human RGS9.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  77 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RGS9

• NCBI Official Name:

  Regulator of G-protein signaling 9

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, J., et al. Carcinogenesis 31 (10) :1755-1761 (2010)

• Background Reference 02:

  Celver, J., et al. J. Neurochem. 114 (3) :739-749 (2010)

• Background Reference 03:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 04:

  Greenbaum, L., et al. Psychiatr. Genet. 20 (1) :47-48 (2010)

• Other Product Names:

  Regulator of G-protein signaling 9, RGS9, RGS9

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid