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RGS5 Antibody

CAT: 0223-58-079Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-079Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
8490
Swiss Prot
O15539
Accession Number
O15539
Host
Rabbit
Reactivity
Human
Immunogen
This RGS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human RGS5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Symbol
RGS5
NCBI Official Name
Regulator of G-protein signaling 5
NCBI Organism
Homo sapiens
Background Reference 01
Wang, J., et al. Carcinogenesis 31 (10) :1755-1761 (2010)
Background Reference 02
Li, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (31) :13818-13823 (2010)
Background Reference 03
Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)
Background Reference 04
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Other Product Names
Regulator of G-protein signaling 5, RGS5, RGS5
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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