NPFFR1 Antibody

• Background:

  Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

• NCBI Gene ID:

  64106

• Swiss Prot:

  Q9GZQ6

• Accession Number:

  Q9GZQ6

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NPFFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human NPFFR1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NPFFR1

• NCBI Official Name:

  Neuropeptide FF receptor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Ubuka, T., et al. PLoS ONE (12), E8400 (2009) :

• Background Reference 03:

  Dowal, L., et al. J. Biol. Chem. 281 (33) :23999-24014 (2006)

• Background Reference 04:

  Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

• Other Product Names:

  Neuropeptide FF receptor 1, G-protein coupled receptor 147, RFamide-related peptide receptor OT7T022, NPFFR1, GPR147, NPFF1

• Tested Applications:

  WB

• Protein ID:

  13878599

• Physical Properties:

  Liquid