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HIC1 Antibody

CAT: 0223-57-498Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-498Size:400 µL
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Background
This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
3090
Swiss Prot
Q14526
Accession Number
Q14526
Host
Rabbit
Reactivity
Human
Immunogen
This HIC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-527 amino acids from the C-terminal region of human HIC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HIC1
NCBI Official Name
Hypermethylated in cancer 1 protein
NCBI Organism
Homo sapiens
Background Reference 01
Pehlivan, S., et al. Cancer Genet. Cytogenet. 201 (2) :128-132 (2010)
Background Reference 02
Van Rechem, C., et al. Mol. Cell. Biol. 30 (16) :4045-4059 (2010)
Background Reference 03
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 04
Zhang, B., et al. Mol. Endocrinol. 23 (12) :2075-2085 (2009)
Other Product Names
Hypermethylated in cancer 1 protein, Hic-1, Zinc finger and BTB domain-containing protein 29, HIC1, ZBTB29
Tested Applications
WB
Protein ID
296439502
Physical Properties
Liquid

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