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AKR1B10 Antibody

CAT: 0223-57-496Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-496Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
NCBI Gene ID
57016
Swiss Prot
O60218
Accession Number
O60218
Host
Rabbit
Reactivity
Human
Immunogen
This AKR1B10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the Central region of human AKR1B10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AKR1B10
NCBI Official Name
Aldo-keto reductase family 1 member B10
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Kropotova, E.S., et al. Mol. Biol. (Mosk.) 44 (2) :243-250 (2010)
Background Reference 03
Heringlake, S., et al. J. Hepatol. 52 (2) :220-227 (2010)
Background Reference 04
Ravindranath, T.M., et al. J. Immunol. 183 (12) :8128-8137 (2009)
Other Product Names
Aldo-keto reductase family 1 member B10, 111-, ARL-1, Aldose reductase-like, Aldose reductase-related protein, ARP, hARP, Small intestine reductase, SI reductase, AKR1B10, AKR1B11
Tested Applications
WB
Physical Properties
Liquid

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