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AKR1B1 Antibody

CAT: 0223-30-373Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-30-373Size:100 µL
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Background
AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
231
Swiss Prot
P15121
Accession Number
NP_001619
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AKR1B1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store AKR1B1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
36 kDa
Applications Notes
AKR1B1 antibody can be used for detection of AKR1B1 by ELISA at 1:312500. AKR1B1 antibody can be used for detection of AKR1B1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
AKR1B1
NCBI Official Name
Aldo-keto reductase family 1, member B1 (aldose reductase)
NCBI Organism
Homo sapiens
Background Reference 01
Steuber, H., (2008) J. Mol. Biol. 379 (5), 991-1016.
Other Product Names
AKR1B1, ADR, ALDR1, ALR2, AR, MGC1804
Tested Applications
ELISA, WB
Protein ID
4502049
Physical Properties
Liquid

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