Products for Research Use Only
RegisterLogin

IBSP Antibody

CAT: 0223-57-486Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-57-486Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
NCBI Gene ID
3381
Swiss Prot
P21815
Accession Number
P21815
Host
Rabbit
Reactivity
Human
Immunogen
This IBSP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human IBSP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
IBSP
NCBI Official Name
Bone sialoprotein 2
NCBI Organism
Homo sapiens
Background Reference 01
Giroux, S., et al. Bone 47 (5) :975-981 (2010)
Background Reference 02
Koller, D.L., et al. J. Clin. Endocrinol. Metab. 95 (4) :1802-1809 (2010)
Background Reference 03
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 04
Gordon, J.A., et al. J. Cell. Biochem. 107 (6) :1118-1128 (2009)
Other Product Names
Bone sialoprotein 2, Bone sialoprotein II, BSP II, Cell-binding sialoprotein, Integrin-binding sialoprotein, IBSP, BNSP
Tested Applications
WB
Protein ID
317373545
Physical Properties
Liquid

Related Products

CatalogName
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody
15-580POMGNT2 Antibody
35-153Cytomegalovirus Antibody

Alternative Products

CatalogName
70R-1687IBSP antibody

Popular Products