GTF2E2 Antibody

• Background:

  GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

• NCBI Gene ID:

  2961

• Swiss Prot:

  P29084

• Accession Number:

  P29084

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GTF2E2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the C-terminal region of human GTF2E2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  33 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GTF2E2

• NCBI Official Name:

  Transcription initiation factor IIE subunit beta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cirulli, E.T., et al. Eur. J. Hum. Genet. 18 (7) :815-820 (2010)

• Background Reference 02:

  Festen, E.A., et al. Am. J. Gastroenterol. 105 (2) :395-402 (2010)

• Background Reference 03:

  Tanaka, A., et al. Genes Cells 14 (3) :395-405 (2009)

• Background Reference 04:

  Jawhari, A., et al. EMBO Rep. 7 (5) :500-505 (2006)

• Other Product Names:

  Transcription initiation factor IIE subunit beta, TFIIE-beta, General transcription factor IIE subunit 2, GTF2E2, TF2E2

• Tested Applications:

  WB

• Protein ID:

  135232

• Physical Properties:

  Liquid