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TARBP2 Antibody

CAT: 0223-57-481Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-481Size:400 µL
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Background
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
NCBI Gene ID
6895
Swiss Prot
Q15633
Accession Number
Q15633
Host
Rabbit
Reactivity
Human
Immunogen
This TARBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human TARBP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Symbol
TARBP2
NCBI Official Name
RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}
NCBI Organism
Homo sapiens
Background Reference 01
Garre, P., et al. Nat. Genet. 42 (10) :817-818 (2010)
Background Reference 02
Wilker, E.H., et al. Environ. Health Perspect. 118 (7) :943-948 (2010)
Background Reference 03
Boni, V., et al. Pharmacogenomics J. (2010) In press :
Background Reference 04
Wang, H.W., et al. Nat. Struct. Mol. Biol. 16 (11) :1148-1153 (2009)
Other Product Names
RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TRBP
Tested Applications
WB, IHC-P
Protein ID
209572714
Physical Properties
Liquid

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