TARDBP Antibody

• Background:

  HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

• NCBI Gene ID:

  23435

• Swiss Prot:

  Q13148

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TARDBP (NP_031401.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 42kDa

• Fragment:

  IgG

• Symbol:

  TARDBP

• Positive Control 2:

  Jurkat

• Positive Control 3:

  SW620

• Positive Control 4:

  HT-29

• Positive Control 5:

  A-673

• Positive Control 6:

  Es-2

• NCBI Official Name:

  TAR DNA binding protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TDP43 Antibody: ALS10, TDP-43, TDP43, TAR DNA-binding protein 43

• Tested Applications:

  WB, IHC, IF, IP, RIP

• Physical Properties:

  Liquid