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NMNAT3 Antibody

CAT: 0223-57-468Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-468Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca (2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]) .
NCBI Gene ID
349565
Swiss Prot
Q96T66
Accession Number
Q96T66
Host
Rabbit
Reactivity
Human
Immunogen
This NMNAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from the Central region of human NMNAT3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NMNAT3
NCBI Official Name
Nicotinamide mononucleotide adenylyltransferase 3
NCBI Organism
Homo sapiens
Background Reference 01
Di Stefano, M., et al. Blood Cells Mol. Dis. 45 (1) :33-39 (2010)
Background Reference 02
Lau, C., et al. J. Biol. Chem. 285 (24) :18868-18876 (2010)
Background Reference 03
Sorci, L., et al. Biochemistry 46 (16) :4912-4922 (2007)
Background Reference 04
Berger, F., et al. J. Biol. Chem. 280 (43) :36334-36341 (2005)
Other Product Names
Nicotinamide mononucleotide adenylyltransferase 3, NMN adenylyltransferase 3, Nicotinate-nucleotide adenylyltransferase 3, NaMN adenylyltransferase 3, Pyridine nucleotide adenylyltransferase 3, PNAT-3, NMNAT3
Tested Applications
WB
Protein ID
116242680
Physical Properties
Liquid

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