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UBP1 Antibody

CAT: 0223-57-457Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-457Size:400 µL
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Background
UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity) . Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
NCBI Gene ID
7342
Swiss Prot
Q9NZI7
Accession Number
Q9NZI7
Host
Rabbit
Reactivity
Human
Immunogen
This UBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the Central region of human UBP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Symbol
UBP1
NCBI Official Name
Upstream-binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Katsura, A., et al. Genes Cells 14 (10) :1183-1196 (2009)
Background Reference 02
Koutnikova, H., et al. PLoS Genet. (8), E1000591 (2009) :
Background Reference 03
Henderson, Y.C., et al. DNA Cell Biol. 27 (2) :71-79 (2008)
Background Reference 04
Huang, N., et al. Mol. Endocrinol. 19 (2) :409-420 (2005)
Other Product Names
Upstream-binding protein 1, Transcription factor LBP-1, UBP1, LBP1
Tested Applications
WB, IHC-P, IF
Protein ID
74719655
Physical Properties
Liquid

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