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SYT5 Antibody

CAT: 0223-57-456Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-456Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SYT5 may be involved in Ca (2+) -dependent exocytosis of secretory vesicles through Ca (2+) and phospholipid binding to the C2 domain or may serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca (2+) -dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity) .
NCBI Gene ID
6861
Swiss Prot
O00445
Accession Number
O00445
Host
Rabbit
Reactivity
Human
Immunogen
This SYT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the Central region of human SYT5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SYT5
NCBI Official Name
Synaptotagmin-5
NCBI Organism
Homo sapiens
Background Reference 01
Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :
Background Reference 02
Sreenath, A.S., et al. Clin. Biochem. 38 (5) :436-443 (2005)
Background Reference 03
Mizutani, A., et al. J. Biol. Chem. 275 (13) :9823-9831 (2000)
Background Reference 04
Craxton, M., et al. FEBS Lett. 460 (3) :417-422 (1999)
Other Product Names
Synaptotagmin-5, Synaptotagmin V, SytV, SYT5
Tested Applications
WB
Physical Properties
Liquid

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