SYT4 Antibody

• Background:

  SYT4 may be involved in Ca (2+) -dependent exocytosis of secretory vesicles through Ca (2+) and phospholipid binding to the C2 domain or may serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis.

• NCBI Gene ID:

  6860

• Swiss Prot:

  Q9H2B2

• Accession Number:

  Q9H2B2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SYT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human SYT4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SYT4

• NCBI Official Name:

  Synaptotagmin-4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)

• Background Reference 02:

  Sonuga-Barke, E.J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :

• Background Reference 03:

  Ferguson, G.D., et al. J. Biol. Chem. 275 (47) :36920-36926 (2000)

• Background Reference 04:

  Mizutani, A., et al. J. Biol. Chem. 275 (13) :9823-9831 (2000)

• Other Product Names:

  Synaptotagmin-4, Synaptotagmin IV, SytIV, SYT4, KIAA1342

• Tested Applications:

  WB

• Protein ID:

  18202937

• Physical Properties:

  Liquid