CSTF3 Antibody

CAT: 0223-57-449Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-449Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF) . This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
1479
Swiss Prot
Q12996
Accession Number
Q12996
Host
Rabbit
Reactivity
Human
Immunogen
This CSTF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-585 amino acids from the C-terminal region of human CSTF3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CSTF3
NCBI Official Name
Cleavage stimulation factor subunit 3
NCBI Organism
Homo sapiens
Background Reference 01
Hockert, J.A., et al. J. Biol. Chem. 285 (1) :695-704 (2010)
Background Reference 02
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 03
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 04
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
Cleavage stimulation factor subunit 3, CF-1 77 kDa subunit, Cleavage stimulation factor 77 kDa subunit, CSTF 77 kDa subunit, CstF-77, CSTF3
Tested Applications
WB
Protein ID
71153231
Physical Properties
Liquid

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