Products for Research Use Only

GRIA3 Antibody

CAT: 0223-57-436Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-57-436Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) -sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G) . Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
NCBI Gene ID
2892
Swiss Prot
P42263
Accession Number
P42263
Host
Rabbit
Reactivity
Human
Immunogen
This GRIA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the N-terminal region of human GRIA3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
101 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GRIA3
NCBI Official Name
Glutamate receptor 3
NCBI Organism
Homo sapiens
Background Reference 01
Ripka, S., et al. Neoplasia 12 (8) :659-667 (2010)
Background Reference 02
Liu, Q., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 26 (4) :376-378 (2010)
Background Reference 03
Feyissa, A.M., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 34 (2) :279-283 (2010)
Background Reference 04
Marek, G.J., et al. Mol. Pharmacol. 77 (3) :317-326 (2010)
Other Product Names
Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3, GluA3, GRIA3, GLUR3, GLURC
Tested Applications
WB
Protein ID
77416864
Physical Properties
Liquid

Alternative Products