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GRIA4 Antibody

CAT: 0223-15-792Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-15-792Size:100 µL
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Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) -sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G) . Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
NCBI Gene ID
2893
Swiss Prot
P48058
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 254-433 of human GRIA4 (NP_001070712.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 101kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:4000
Symbol
GRIA4
Positive Control 2
B cells
Positive Control 3
Mouse brain
Positive Control 4
Mouse liver
Positive Control 5
Mouse kidney
Positive Control 6
Mouse spinal cord
NCBI Official Name
Glutamate receptor, ionotropic, AMPA 4
NCBI Organism
Homo sapiens
Other Product Names
GRIA4, glutamate receptor, ionotrophic, AMPA 4, GLUR4, GLUR4C, GLURD, AMPA-selective glutamate receptor 4
Tested Applications
WB
Physical Properties
Liquid

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