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GABPA Antibody

CAT: 0223-57-435Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-435Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
2551
Swiss Prot
Q06546
Accession Number
Q06546
Host
Rabbit
Reactivity
Human
Immunogen
This GABPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the Central region of human GABPA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GABPA
NCBI Official Name
GA-binding protein alpha chain
NCBI Organism
Homo sapiens
Background Reference 01
Henderson, A.J., et al. Thorax 65 (10) :897-902 (2010)
Background Reference 02
Eynon, N., et al. Physiol. Genomics 41 (1) :78-81 (2010)
Background Reference 03
Levy, S., et al. IUBMB Life 62 (3) :237-246 (2010)
Background Reference 04
Kim, Y.R., et al. J. Pathol. 220 (4) :446-451 (2010)
Other Product Names
GA-binding protein alpha chain, GABP subunit alpha, Nuclear respiratory factor 2 subunit alpha, Transcription factor E4TF1-60, GABPA, E4TF1A
Tested Applications
WB
Protein ID
729553
Physical Properties
Liquid

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