ODC1 Antibody

• Background:

  This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.

• NCBI Gene ID:

  4953

• Swiss Prot:

  P11926

• Accession Number:

  P11926

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ODC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of human ODC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ODC1

• NCBI Official Name:

  Ornithine decarboxylase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chaturvedi, R., et al. Gastroenterology 139 (5) :1686-1698 (2010)

• Background Reference 02:

  Zell, J.A., et al. J. Natl. Cancer Inst. 102 (19) :1513-1516 (2010)

• Background Reference 03:

  Geerts, D., et al. Int. J. Cancer 126 (9) :2012-2024 (2010)

• Background Reference 04:

  Hughes, D., et al. Colorectal Dis (2010) In press :

• Other Product Names:

  Ornithine decarboxylase, ODC, ODC1

• Tested Applications:

  WB

• Protein ID:

  118377

• Physical Properties:

  Liquid