PPCDC Antibody

• Background :

  Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]) .

• NCBI Gene ID :

  60490

• Swiss Prot :

  Q96CD2

• Accession Number :

  Q96CD2

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  This PPCDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PPCDC.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  22 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  PPCDC

• NCBI Official Name :

  Phosphopantothenoylcysteine decarboxylase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Strauss, E., et al. Biochemistry 43 (49) :15520-15533 (2004)

• Background Reference 02 :

  Manoj, N., et al. Acta Crystallogr.Biol. Crystallogr. 59 (PT 10), 1762-1766 (2003) :

• Background Reference 03 :

  Daugherty, M., et al. J. Biol. Chem. 277 (24) :21431-21439 (2002)

• Other Product Names :

  Phosphopantothenoylcysteine decarboxylase, PPC-DC, CoaC, PPCDC, COAC

• Tested Applications :

  WB

• Protein ID :

  296434457

• Physical Properties :

  Liquid