PLSCR4 Antibody

• Background:

  PLSCR4 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

• NCBI Gene ID:

  57088

• Swiss Prot:

  Q9NRQ2

• Accession Number:

  Q9NRQ2

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This PLSCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human PLSCR4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  37 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PLSCR4

• NCBI Official Name:

  Phospholipid scramblase 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Sahu, S.K., et al. Biochim. Biophys. Acta 1790 (10) :1274-1281 (2009)

• Background Reference 03:

  Py, B., et al. PLoS ONE (3), E5006 (2009) :

• Background Reference 04:

  Shibata, H., et al. J. Biol. Chem. 283 (15) :9623-9632 (2008)

• Other Product Names:

  Phospholipid scramblase 4, PL scramblase 4, Ca (2+) -dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, TRA1, PLSCR4

• Tested Applications:

  WB, IHC-P

• Protein ID:

  212276457

• Physical Properties:

  Liquid