ERG25 Antibody

• Background:

  Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

• NCBI Gene ID:

  6307

• Swiss Prot:

  Q15800

• Accession Number:

  Q15800

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ERG25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-293 amino acids from the C-terminal region of human ERG25.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MSMO1

• NCBI Official Name:

  Methylsterol monooxygenase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)

• Background Reference 02:

  Lim, J., et al. Cell 125 (4) :801-814 (2006)

• Background Reference 03:

  Li, L., et al. J. Biol. Chem. 271 (28) :16927-16933 (1996)

• Other Product Names:

  Methylsterol monooxygenase 1, C-4 methylsterol oxidase, MSMO1, DESP4, ERG25, SC4MOL

• Tested Applications:

  WB, IHC-P

• Protein ID:

  2498340

• Physical Properties:

  Liquid