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MIST Antibody

CAT: 0223-57-368Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-368Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515) . MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420) -mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140) -mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]) .
NCBI Gene ID
116449
Swiss Prot
Q7Z7G1
Accession Number
Q7Z7G1
Host
Rabbit
Reactivity
Human
Immunogen
This MIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human MIST.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CLNK
NCBI Official Name
Cytokine-dependent hematopoietic cell linker
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Cronin, S., et al. Eur. J. Hum. Genet. 17 (2) :213-218 (2009)
Background Reference 03
Goitsuka, R., et al. J. Biol. Chem. 276 (38) :36043-36050 (2001)
Background Reference 04
Goitsuka, R., et al. Int. Immunol. 12 (4) :573-580 (2000)
Other Product Names
Cytokine-dependent hematopoietic cell linker, Mast cell immunoreceptor signal transducer, CLNK, MIST
Tested Applications
WB
Protein ID
166217263
Physical Properties
Liquid

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