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DAO Antibody

CAT: 0223-57-366Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-366Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
NCBI Gene ID
1610
Swiss Prot
P14920
Accession Number
P14920
Host
Rabbit
Reactivity
Human
Immunogen
This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human DAO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DAO
NCBI Official Name
D-amino-acid oxidase
NCBI Organism
Homo sapiens
Background Reference 01
Kim, B., et al. Psychiatry Res 179 (2) :121-125 (2010)
Background Reference 02
Caldinelli, L., et al. Protein Sci. 19 (8) :1500-1512 (2010)
Background Reference 03
Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)
Background Reference 04
Ohnuma, T., et al. Schizophr. Res. 118 (1-3), 300-302 (2010) :
Other Product Names
D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX
Tested Applications
WB
Protein ID
25453448
Physical Properties
Liquid

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