Products for Research Use Only

ABP1 Antibody

CAT: 0223-57-365Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-365Size:400 µL
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Background
This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
NCBI Gene ID
26
Swiss Prot
P19801
Accession Number
P19801
Host
Rabbit
Reactivity
Human
Immunogen
This ABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human ABP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
85 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AOC1
NCBI Official Name
Amiloride-sensitive amine oxidase [copper-containing]
NCBI Organism
Homo sapiens
Background Reference 01
Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)
Background Reference 02
McGrath, A.P., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 66 (PT 2), 137-142 (2010) :
Background Reference 03
Chambers, J.C., et al. Nat. Genet. 42 (2) :149-152 (2010)
Background Reference 04
McGrath, A.P., et al. Biochemistry 48 (41) :9810-9822 (2009)
Other Product Names
Amiloride-sensitive amine oxidase [copper-containing], DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, AOC1, ABP1, DAO1
Tested Applications
WB
Protein ID
251757489
Physical Properties
Liquid