ABP1 Antibody

• Background:

  This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

• NCBI Gene ID:

  26

• Swiss Prot:

  P19801

• Accession Number:

  P19801

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human ABP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  85 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  AOC1

• NCBI Official Name:

  Amiloride-sensitive amine oxidase [copper-containing]

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

• Background Reference 02:

  McGrath, A.P., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 66 (PT 2), 137-142 (2010) :

• Background Reference 03:

  Chambers, J.C., et al. Nat. Genet. 42 (2) :149-152 (2010)

• Background Reference 04:

  McGrath, A.P., et al. Biochemistry 48 (41) :9810-9822 (2009)

• Other Product Names:

  Amiloride-sensitive amine oxidase [copper-containing], DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, AOC1, ABP1, DAO1

• Tested Applications:

  WB

• Protein ID:

  251757489

• Physical Properties:

  Liquid