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Mouse Ntrk2 Antibody

CAT: 0223-57-360Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-360Size:400 µL
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Background
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF) . Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
NCBI Gene ID
18212
Swiss Prot
P15209
Accession Number
P15209
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Ntrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the Central region of mouse Ntrk2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
92 kDa
Fragment
Rabbit Ig
Symbol
Ntrk2
NCBI Official Name
BDNF/NT-3 growth factors receptor
NCBI Organism
Mus musculus
Background Reference 01
Xu, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (44) :19126-19131 (2010)
Background Reference 02
Lobo, M.K., et al. Science 330 (6002) :385-390 (2010)
Background Reference 03
Gascon, E., et al. J. Neurosci. 30 (37) :12414-12423 (2010)
Background Reference 04
Nikoletopoulou, V., et al. Nature 467 (7311) :59-63 (2010)
Other Product Names
BDNF/NT-3 growth factors receptor, GP145-TrkB/GP95-TrkB, Trk-B, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Ntrk2, Trkb
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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