Mouse Mknk2 Antibody

• Background:

  Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity) .

• NCBI Gene ID:

  17347

• Swiss Prot:

  Q8CDB0

• Accession Number:

  Q8CDB0

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of mouse Mknk2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  52 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Mknk2

• NCBI Official Name:

  MAP kinase-interacting serine/threonine-protein kinase 2

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Ueda, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :13984-13990 (2010)

• Background Reference 02:

  Furic, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :14134-14139 (2010)

• Background Reference 03:

  Joshi, S., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (29) :12097-12102 (2009)

• Background Reference 04:

  Chrestensen, C.A., et al. Genes Cells 12 (10) :1133-1140 (2007)

• Other Product Names:

  MAP kinase-interacting serine/threonine-protein kinase 2, MAP kinase signal-integrating kinase 2, MAPK signal-integrating kinase 2, Mnk2, Mknk2, Mnk2

• Tested Applications:

  WB

• Physical Properties:

  Liquid