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XPA Antibody

CAT: 0223-57-303Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-303Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
NCBI Gene ID
7507
Swiss Prot
P23025
Accession Number
P23025
Host
Rabbit
Reactivity
Human
Immunogen
This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the C-terminal region of human XPA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
XPA
NCBI Official Name
DNA repair protein complementing XP-A cells
NCBI Organism
Homo sapiens
Background Reference 01
Palli, D., et al. Mutagenesis 25 (6) :569-575 (2010)
Background Reference 02
Fan, W., et al. Mol. Cell 39 (2) :247-258 (2010)
Background Reference 03
Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
Background Reference 04
Hsieh, Y.Y., et al. Anticancer Res. 30 (6) :2203-2208 (2010)
Other Product Names
DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein, XPA, XPAC
Tested Applications
WB
Protein ID
139816
Physical Properties
Liquid

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