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G3BP1 Antibody

CAT: 0223-57-271Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-271Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
NCBI Gene ID
10146
Swiss Prot
Q13283
Accession Number
Q13283
Host
Rabbit
Reactivity
Human
Immunogen
This G3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human G3BP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Symbol
G3BP1
NCBI Official Name
Ras GTPase-activating protein-binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Gao, X., et al. FEBS Lett. 584 (16) :3525-3532 (2010)
Background Reference 02
Ortega, A.D., et al. J. Cell. Sci. 123 (PT 16), 2685-2696 (2010) :
Background Reference 03
Hinton, S.D., et al. Biochem. J. 427 (3) :349-357 (2010)
Background Reference 04
Shim, J.H., et al. Cancer Prev Res (Phila) 3 (5) :670-679 (2010)
Other Product Names
Ras GTPase-activating protein-binding protein 1, G3BP-1, ATP-dependent DNA helicase VIII, hDH VIII, GAP SH3 domain-binding protein 1, G3BP1, G3BP
Tested Applications
WB, IHC-P
Protein ID
14916572
Physical Properties
Liquid

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