NAPSA Antibody

• Background:

  The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. [provided by RefSeq].

• NCBI Gene ID:

  9476

• Swiss Prot:

  O96009

• Accession Number:

  O96009

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NAPSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-397 amino acids from the C-terminal region of human NAPSA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NAPSA

• NCBI Official Name:

  Napsin-A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bishop, J.A., et al. Hum. Pathol. 41 (1) :20-25 (2010)

• Background Reference 02:

  Woischnik, M., et al. Eur. Respir. J. 31 (6) :1197-1204 (2008)

• Background Reference 03:

  Ueno, T., et al. Lab. Invest. 88 (3) :256-263 (2008)

• Background Reference 04:

  Innocenti, M., et al. Nat. Cell Biol. 6 (4) :319-327 (2004)

• Other Product Names:

  Napsin-A, 3423-, Aspartyl protease 4, ASP4, Asp 4, Napsin-1, TA01/TA02, NAPSA, NAP1, NAPA

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid