CTAG2 Antibody

• Background:

  This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID 10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq].

• NCBI Gene ID:

  30848

• Swiss Prot:

  O75638

• Accession Number:

  O75638

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CTAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-149 amino acids from the Central region of human CTAG2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  21 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CTAG2

• NCBI Official Name:

  Cancer/testis antigen 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, X.Y., et al. Oncol. Rep. 21 (3) :713-719 (2009)

• Background Reference 02:

  Shao, Y., et al. J. Cancer Res. Clin. Oncol. 134 (4) :495-502 (2008)

• Background Reference 03:

  Andrade, V.C., et al. Cancer Immun. 8, (2008) :

• Background Reference 04:

  Kan, T., et al. Oncology 70 (1) :25-33 (2006)

• Other Product Names:

  Cancer/testis antigen 2, CT2, Autoimmunogenic cancer/testis antigen NY-ESO-2, Cancer/testis antigen 62, CT62, L antigen family member 1, LAGE-1, CTAG2, ESO2, LAGE1

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid