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ARHGDIB Antibody

CAT: 0223-57-239Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-239Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs) . The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]) .
NCBI Gene ID
397
Swiss Prot
P52566
Accession Number
P52566
Host
Rabbit
Reactivity
Human
Immunogen
This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human ARHGDIB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Symbol
ARHGDIB
NCBI Official Name
Rho GDP-dissociation inhibitor 2
NCBI Organism
Homo sapiens
Background Reference 01
Niu, H., et al. Oncol. Rep. 24 (2) :465-471 (2010)
Background Reference 02
Zhen, H., et al. Int. J. Gynecol. Cancer 20 (3) :316-322 (2010)
Background Reference 03
Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)
Background Reference 04
Said, N., et al. Cancer Metastasis Rev. 28 (3-4), 327-333 (2009) :
Other Product Names
Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta, ARHGDIB, GDIA2, GDID4, RAP1GN1
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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