ARHGDIA Antibody

• Background:

  This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

• NCBI Gene ID:

  396

• Swiss Prot:

  P52565

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human ARHGDIA (NP_001172006.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 23kDa

• Fragment:

  IgG

• Symbol:

  ARHGDIA

• Positive Control 2:

  U-251MG

• Positive Control 3:

  293T

• Positive Control 4:

  HepG2

• Positive Control 5:

  H460

• Positive Control 6:

  K-562

• NCBI Official Name:

  Rho GDP dissociation inhibitor (GDI) alpha

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ARHGDIA, RHOGDI-1, RHOGDI, Rho GDP dissociation inhibitor (GDI) alpha, MGC117248, GDIA1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid