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ICAM3 Antibody

CAT: 0223-57-213Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-213Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.
NCBI Gene ID
3385
Swiss Prot
P32942
Accession Number
P32942
Host
Rabbit
Reactivity
Human
Immunogen
This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the Central region of human ICAM3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ICAM3
NCBI Official Name
Intercellular adhesion molecule 3
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)
Background Reference 03
Mosbruger, T.L., et al. J. Infect. Dis. 201 (9) :1371-1380 (2010)
Background Reference 04
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)
Other Product Names
Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3
Tested Applications
WB
Protein ID
206729872
Physical Properties
Liquid

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