ICAM2 Antibody

• Background :

  The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.

• NCBI Gene ID :

  3384

• Swiss Prot :

  P13598

• Accession Number :

  P13598

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  31 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ICAM2

• NCBI Official Name :

  Intercellular adhesion molecule 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

• Background Reference 02 :

  Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

• Background Reference 03 :

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 04 :

  Sato, H., et al. Biochim. Biophys. Acta 1790 (10) :1198-1205 (2009)

• Other Product Names :

  Intercellular adhesion molecule 2, ICAM-2, CD102, ICAM2

• Tested Applications :

  WB, Flow

• Protein ID :

  115502404

• Physical Properties :

  Liquid