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ICAM2 Antibody

CAT: 0223-55-586Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-586Size:400 µL
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Background
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
3384
Swiss Prot
P13598
Accession Number
P13598
Host
Rabbit
Reactivity
Human
Immunogen
This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
ICAM2
NCBI Official Name
Intercellular adhesion molecule 2
NCBI Organism
Homo sapiens
Background Reference 01
Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)
Background Reference 02
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)
Background Reference 03
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 04
Sato, H., et al. Biochim. Biophys. Acta 1790 (10) :1198-1205 (2009)
Other Product Names
Intercellular adhesion molecule 2, ICAM-2, CD102, ICAM2
Tested Applications
WB, Flow
Protein ID
115502404
Physical Properties
Liquid

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