DOLPP1 Antibody

• Background:

  DOLPP1 is required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity) .

• NCBI Gene ID:

  57171

• Swiss Prot:

  Q86YN1

• Accession Number:

  Q86YN1

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This DOLPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the C-terminal region of human DOLPP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  27 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DOLPP1

• NCBI Official Name:

  Dolichyldiphosphatase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Humphray, S.J., et al. Nature 429 (6990) :369-374 (2004)

• Background Reference 02:

  Rush, J.S., et al. J. Biol. Chem. 277 (47) :45226-45234 (2002)

• Background Reference 03:

  Gilley, J., et al. Hum. Mol. Genet. 8 (7) :1313-1320 (1999)

• Background Reference 04:

  Wedgwood, J.F., et al. J. Biol. Chem. 255 (3) :1120-1123 (1980)

• Other Product Names:

  Dolichyldiphosphatase 1, Dolichyl pyrophosphate phosphatase 1, DOLPP1, LSFR2

• Tested Applications:

  WB

• Protein ID:

  45476905

• Physical Properties:

  Liquid